Upstream Bio, Inc.
Financial highlights
| Metric | FY 12/31/25 | FY 12/31/24 | FY 12/31/23 | FY 12/31/22 |
|---|---|---|---|---|
| Income Statement | ||||
| Revenue | $2.9 | $2.4 | $2.4 | — |
| Operating income | -$160.4 | -$77.8 | -$40.1 | — |
| Net income | -$143.4 | -$62.8 | -$20.5 | — |
| Cash Flow Statement | ||||
| Free cash flow | -$133.4 | -$59.7 | -$38.1 | — |
Shares outstanding 54.4M · Free float 63.4%
Annual filing data through FY ended December 31, 2025; float as of July 16, 2026.