The Tip Desk

Spyre Therapeutics, Inc.

Financial highlights

Amounts in millions
MetricFY 12/31/25FY 12/31/24FY 12/31/23FY 12/31/22FY 12/31/21
Income Statement
Revenue$0.0$0.0$0.9$2.3$18.7
Operating income-$209.6-$208.6-$242.3-$84.8-$65.6
Net income-$155.2-$208.0-$338.8-$83.8-$65.8
Cash Flow Statement
Free cash flow—-$157.4-$99.9-$80.2-$54.3
Dividends$0.0$0.0$0.0$0.0$0.0

Shares outstanding 88.2M · Free float 64.8%

Annual filing data through FY ended December 31, 2025; float as of October 1, 2026.

Coverage