The Tip Desk

IONIS PHARMACEUTICALS INC

Financial highlights

Amounts in millions
MetricFY 12/31/25FY 12/31/24FY 12/31/23FY 12/31/22FY 12/31/21
Income Statement
Revenue$943.7$705.1$787.6$587.4$810.5
Operating income-$381.7-$475.1-$353.7-$410.2-$30.2
Net income-$381.4-$453.9-$366.3-$269.7-$28.6
Cash Flow Statement
Free cash flow-$320.0-$546.2-$331.3-$290.1$18.8
Share repurchases———$0.0$0.0

Shares outstanding 166.2M · Free float 99.3%

Annual filing data through FY ended December 31, 2025; float as of October 8, 2026.

Earnings

Other Coverage